Lactoferrin, which is high in colostrum and cow’s milk, is a protein bound to iron. Lactoferrin is involved in iron transport, antibacterial, antioxidant, and immune regulation, and its proper consumption can contribute to good health. However, long-term and excessive consumption of lactoferrin may have certain harmful effects. Firstly, lactoferrin can help in iron transport, and if excessive supplementation of lactoferrin leads to excessive iron transport and absorption, it may cause digestive disorders and affect the absorption of other nutrients. Second, always consuming purified lactoferrin can interfere with the absorption of normal proteins in the gut. Because purified food is more refined, the digestive burden on the gastrointestinal tract is small, but in the long run it is actually detrimental to digestion and can easily lead to low digestive system function, constipation, and the occurrence of gastrointestinal allergies and other diseases. Currently, lactoferrin is used as a special formula for children with iron deficiency anemia and immune deficiency, and there is no need for healthy people to consume lactoferrin for a long time. If you want to replenish iron, antibacterial, and regulate immunity, it is possible to consume lactoferrin appropriately, but once consumed in excess, even as a substitute for infant formula, it may backfire and cause some harm.