Felodipine extended-release tablets and timosartan can be taken at the same time, the two taken together have a superimposed effect, helping to control blood pressure, the use of medication should follow the doctor’s instructions. Felodipine extended-release tablets is a calcium channel blocker class of antihypertensive drugs, the drug can make the peripheral vascular resistance down and reduce blood pressure, suitable for the treatment of hypertension, the dosage should be individualized. It is contraindicated in women during pregnancy, patients with acute myocardial infarction, unstable angina, decompensated heart failure, and those who are allergic to felodipine and its components. Adverse reactions are mainly ankle edema, headache, facial flushing and fatigue. Timosartan is an angiotensin II receptor antagonist class of antihypertensive drugs, the drug can make vasodilatation at the same time with inhibition of cardiac excitation and renal reabsorption of sodium, inhibition of aldosterone synthesis and release of the role of timosartan has an effective reduction in blood pressure and cardiovascular risk. Adverse reactions mainly include headache, fatigue, allergy and so on. Felodipine extended-release tablets and timosartan can be used in combination, which can effectively enhance the effect of blood pressure reduction, and is suitable for patients whose blood pressure cannot be effectively controlled by a single drug. If the patient has high blood pressure, it is recommended to consult the doctor in time and strictly follow the doctor’s instructions for medication.