Hypoglycemia is a group of diseases characterized by clinical symptoms of lowered blood glucose, including acute and chronic, primary and secondary, with different treatment modalities for different causes. The treatment of hypoglycemia includes two aspects: one is to relieve the symptoms of inadequate neural sugar supply, and the other is to correct the various causes of hypoglycemia. Relieve the inadequate sugar supply to the nervous system: For mild to moderate hypoglycemia, it can be relieved by taking sugar water and sugary drinks orally, or by eating candy, propolis, bread and buns. In severe cases and patients suspected of hypoglycemic coma, blood glucose should be monitored immediately, even without blood glucose results, and given immediately with 50% glucose 60-100ml intravenously, followed by 5%-10% glucose solution intravenously, with hydrocortisone 100mg or glucagon 0.5-1mg intramuscularly or intravenously if necessary. Do not feed the delirious person to prevent respiratory asphyxia. Correct the various causes of hypoglycemia: For drug-related hypoglycemia, the relevant drugs should be stopped in time. People who use insulin or insulin-producing drugs combined with α-glucosidase inhibitors should use pure glucose to treat symptomatic hypoglycemia. Because alpha glucosidase inhibitors slow down the digestion of other carbohydrates, other forms of carbohydrates such as starchy foods and sucrose are unable to correct hypoglycemia in a timely manner. A history of alcohol abuse, systemic related diseases especially tumors, wasting diseases, malnutrition, and history of gastrointestinal surgery should be taken care of from lifestyle habits. Those with suspected insulinoma should be further localized and diagnosed, and surgical resection should be performed for patients with definite insulinoma. Therefore, for the treatment of hypoglycemia, emergency treatment to replenish blood sugar is only one aspect, more important is to find the cause and usual prevention.