The treatment of hand numbness should be individualized according to the specific etiology of the intervention. There are mainly drug therapy, physical therapy and surgical treatment. 1. Carpal tunnel syndrome: reduce wrist joint activities, give local physical therapy, injection of prednisolone acetate, if necessary, take the transverse carpal ligament incision and decompression surgery, nerve bundles between the scar excision neurolysis and other treatments to relieve symptoms. 2. Cervical spondylosis: improve lifestyle, avoid long-term low head work, improve shoulder and neck muscles, if necessary, use appropriate drugs, such as methylcobalamin and other nutritive drugs, can also be relieved by hot compresses, infrared and other ways; serious cases need traction or cervical spinal canal enlargement plasty and other surgical treatments. 3. Peripheral neuritis: no matter what the cause of multiple peripheral neuritis, early and sufficient amount of vitamin B1, vitamin B2, vitamin B6, vitamin B12 and other drugs should be supplemented in order to nourish the nerves. At the same time can be carried out for the cause of the treatment, such as diabetes complications need to be through metformin and other drugs to control blood sugar. Many causes of hand numbness, according to the patient’s specific cause of the disease under the guidance of a doctor to be targeted treatment, do not blindly self-medication.