Renal parenchymal hypertension is a type of secondary hypertension. Patients with renal parenchymal hypertension often have significant proteinuria and hematuria, along with a degree of renal anemia, as well as decreased glomerular filtration rate and increased serum creatinine levels. Patients with essential hypertension, on the other hand, tend to have less pronounced proteinuria and hematuria is rare. In the early stages of essential hypertension, generally speaking, there is no renal damage, but at the end of the disease, there is a gradual decrease in glomerular filtration rate and an increase in serum creatinine, which, in the early stages of the disease, mainly affects the function of renal tubular concentration, but often has little effect on glomerular filtration. In actual clinical practice, it is sometimes difficult to make a clear distinction between essential hypertension and renal hypertension. What is renal hypertension? For example, hypertension caused by diabetic nephropathy, pyelonephritis, polycystic kidney, post-transplantation, and acute and chronic glomerulonephritis, etc. This type of hypertension is called renal parenchymal hypertension. If you want to further clarify whether it is renal parenchymal hypertension, then a histological examination of renal puncture can be performed to help clarify the diagnosis. For patients with renal parenchymal hypertension, salt intake must be strictly limited, and the total recommended salt intake should be less than three grams per day. Patients with renal parenchymal hypertension should be advised to control their blood pressure more strictly, preferably by keeping their systolic blood pressure below 130 mm Hg and diastolic blood pressure below 80 mm Hg. Patients with serum creatinine above 3 mg/dl should be cautiously treated with antihypertensive drugs of the priligy or sartan class. For patients without significant contraindications, a combination antihypertensive regimen should include either a priligy or a sartan, which can help reduce proteinuria and also slow down the deterioration of renal function.