If cardia does not improve after surgery, oral medication can be taken, or endoscopic treatment can be performed after evaluation by a specialized physician. 1. Drug therapy: there are nitrate drugs such as nitroglycerin and calcium antagonists such as nifedipine. These drugs mainly relax the lower esophageal sphincter pressure by inhibiting smooth muscle contraction. Proton pump inhibitors such as omeprazole can also be used to inhibit the secretion of gastric acid to reduce the discomfort caused by excessive gastric acid secretion. 2. Endoscopic treatment: Endoscopic treatment is divided into botulinum toxin injection and dilatation. Dilatation therapy is to dilate the lower esophageal sphincter with a balloon or a stent, thus causing relaxation of the lower esophageal sphincter. Botulinum toxin injection therapy is to inhibit the release of acetylcholine through the binding of botulinum toxin to the presynaptic receptor to achieve the purpose of relaxation of the lower esophageal sphincter. It is recommended to actively seek medical advice, follow the doctor’s instructions for medication and treatment, and at the same time should develop good eating habits, avoid overeating, hunger and satiety. Avoid the use of too spicy, cold stimulating food, pay attention to the regularity of diet. Reasonable rest, appropriate exercise.