The corners of the mouth blisters should hang oral mucosal disease department, if the hospital stomatology department is not subdivided out of the mucosal disease department, you can go to the stomatology department or simple mucosal disease department for treatment. The blisters on the corners of the mouth are mainly caused by the herpes simplex virus when the body’s immune function is low, in the treatment of the first to carry on the antiviral treatment, you can take antiviral Chinese medicine, such as antiviral oral liquid and Banlangen granules, etc., and you can also take the western medicines, such as acyclovir, ganciclovir, and famciclovir, etc., to carry on antiviral treatment, and in the blisters on the corners of the mouth can be applied to the area of acyclovir ointment. Patients with blisters on the corners of the mouth should drink more water, maintain a light, easily digestible diet, take more rest, improve the body’s immunity, avoid spicy, stimulating food stimulation on the corners of the mouth in the diet, at the same time after the blisters on the corners of the mouth to avoid talking, eating, resulting in a wide-open mouth, wide-open mouth will lead to the corners of the mouth more serious trauma.