Any disease is not recommended to stay up late, because staying up late is very damaging to the body and can cause a variety of diseases. Long-term staying up late, sleep deprivation and cancer, obesity, Alzheimer’s disease, Parkinson’s disease, neurasthenia, memory loss, decreased immunity, gastrointestinal disorders, diabetes, hypertension, coronary heart disease, cerebrovascular disease, sudden death and so on. Facts have proved that there are a lot of young people stay up late for a long time, a long time continuous Internet access, serious overtime work, which ultimately led to the tragedy of sudden death. Staying up late can cause endocrine imbalance, decreased immunity, decreased sexual function and spermatogenesis and spermatogenesis, premature ovarian failure, and so on, and in serious cases, it can also lead to infertility. It is recommended that patients do not often stay up late, should ensure adequate sleep, pay attention to rest, to avoid adverse consequences on the human body.