On February 19, 2020, the National Health Commission issued the “New Coronavirus Pneumonia Diagnosis and Treatment Program (Trial Sixth Edition)” (hereinafter referred to as the “Sixth Edition”), which is now interpreted as follows. First, the transmission pathway transmission pathway will be “via respiratory droplets and contact transmission is the main means of transmission” to “via respiratory droplets and close contact transmission is the main means of transmission.” Add the word “close” before the word “contact”. Add “the possibility of transmission via aerosols exists in relatively closed environments with prolonged exposure to high concentrations of aerosols.” Second, the clinical manifestations of severe patients in addition to “rapid progression to acute respiratory distress syndrome, septic shock, difficult to correct metabolic acidosis and coagulation dysfunction”, but also “multi-organ failure”. Laboratory tests, emphasizing that “in order to improve the positive rate of nucleic acid detection, it is recommended that sputum be retained as much as possible, and lower respiratory secretions be collected from patients undergoing tracheal intubation, and specimens be sent for examination as soon as possible after collection.” The sixth edition of the diagnostic criteria canceled the distinction between Hubei Province and other provinces outside Hubei Province. Uniformly divided into “suspected cases” and “confirmed cases” two categories. There are two types of suspected cases. One is “having any one of the epidemiologic history, and meeting any two of the clinical manifestations (fever and/or respiratory symptoms; having the above imaging features of pneumonia; normal or reduced total white blood cell count and reduced lymphocyte count in the early stage of the disease). The second is “without a clear epidemiologic history, and meets three of the clinical manifestations (fever and/or respiratory symptoms; the above imaging features of pneumonia; normal or decreased white blood cell count and decreased lymphocyte count in the early stage of the disease). Confirmed cases need to have positive results of pathogenic evidence (positive nucleic acid detection of novel coronavirus by real-time fluorescence RT-PCR; or viral gene sequencing, which is highly homologous to known novel coronavirus). Clinical classification is still divided into “light, ordinary, heavy and critical”, and the partial pressure of arterial oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300mmHg (1mmHg=0.133kPa) is increased to “high-altitude (more than 1,000 meters above sea level) areas should be”. PaO2/FiO2 should be corrected according to the following formula: PaO2/FiO2 × [atmospheric pressure (mmHg)/760]”. Those with “significant lesion progression >50% within 24-48 hours on lung imaging” were managed as heavy. V. Differential diagnosis: Differential diagnosis of related diseases was proposed according to mild forms of novel coronavirus infection and novel coronavirus pneumonia. Such as new coronavirus infection mild manifestations need to be differentiated from other viruses caused by upper respiratory tract infections; new coronavirus pneumonia and influenza virus, adenovirus, respiratory syncytial virus and other known viral pneumonia and Mycoplasma pneumoniae infection. It is emphasized that “suspected cases should be tested for common respiratory pathogens as far as possible, including rapid antigen detection and multiplex PCR nucleic acid testing.” Deleting “the requirements for the handling of clinically diagnosed cases in Hubei Province”. Delete “suspected cases” exclusion criteria, suspected cases of de-isolation criteria and “de-isolation criteria” are consistent. VII. Treatment 1. Determine the place of treatment according to the condition. Delete “suspected and confirmed cases” and replace it with “should be isolated and treated in designated hospitals with effective isolation and protection conditions, and confirmed cases can be admitted to the same room.” 2. Antiviral treatment: Delete “Currently there is no confirmed effective anti-new coronavirus treatment.” Among the trial drugs, add two drugs, “chloroquine phosphate (500 mg twice daily for adults) and abidol (200 mg three times daily for adults)”. Ribavirin is recommended in combination with interferon or lopinavir/ritonavir. None of the trial medications were to be administered for more than 10 days. Further evaluation of the efficacy of the drugs currently on trial is recommended in clinical practice. Concomitant use of 3 or more antiviral drugs is not recommended and should be discontinued if intolerable side effects occur.3. Treatment of severe and critical cases. Add “plasma therapy for convalescent patients”, which is recommended to be applied to patients with rapid disease progression, severe and critical cases. For dosage, refer to “Clinical Treatment Plan for Recovered Recovered Patients with New Crown Pneumonia Plasma (Trial First Edition)”. 4. Other therapeutic measures: For critically ill patients with high inflammatory response, “the use of extracorporeal blood purification technology can be considered under certain conditions”. Revised to read: “The use of extracorporeal blood purification techniques such as plasma exchange, adsorption, perfusion, blood/plasma filtration, etc. can be considered if conditions exist.” 5. About Chinese medicine treatment. Through in-depth observation and treatment of patients, on the basis of summarizing and analyzing Chinese medicine diagnosis and treatment protocols across the country, sorting out and screening Chinese medicine treatment experiences and effective prescriptions from various places, and combining with the “Notice on Recommending the Use of “Lung Cleansing and Detoxification Soup” in the Combination of Traditional Chinese Medicine and Western Medicine in the Rescue and Treatment of Pneumonia Infected by the New Type of Coronavirus” and the “Diagnosis and Treatment of Severe and Critically Ill Cases of New Type of Coronavirus Pneumonia The “Diagnostic and Treatment Program for Severe and Critical Cases of New Coronavirus Pneumonia (Trial Implementation of the Second Edition)” and the “Code of Practice for the Management of Light and Ordinary Cases of New Coronavirus Pneumonia”, etc., and the “Diagnostic and Treatment Program for Pneumonia Infected by New Coronavirus (Trial Implementation of the Fifth Edition, Revised Edition)” have been adjusted and supplemented. Continuing the staging of the whole course of the disease in the previous edition, the TCM treatment is divided into the medical observation period and the clinical treatment period (confirmed cases), and the clinical treatment period is divided into the light-type, ordinary-type, heavy-type, critical-type, and recovery period. Proprietary Chinese medicines were recommended for the medical observation period. In the clinical treatment period, the generic formula “Lung Clearing and Detoxification Soup” is recommended, and the clinical manifestations, recommended prescription and dosage, and method of administration are described for the light-type, general-type, heavy-type, critical-type, and recovery-phase respectively. At the same time, the specific usage of proprietary Chinese medicines (including Chinese medicine injections) applicable to heavy and critical types has been added to the program. Each region can refer to the recommended program for identification and treatment according to the condition, local climate characteristics and different body qualities. VIII. Release from isolation and post-discharge precautions The criteria for release from isolation should meet the following four conditions: 1) body temperature has returned to normal for more than 3 days; 2) respiratory symptoms have significantly improved; 3) lung imaging shows that acute exudative lesions have significantly absorbed and improved; 4) two consecutive respiratory specimens are negative for nucleic acid (with at least one day interval between the sampling time). Post-discharge precautions” is added: 1. The designated hospitals should do a good job of contacting the primary healthcare institutions in the patient’s place of residence, share medical record information, and push the information of the discharged patients to the neighborhood committees and primary healthcare institutions of the patient’s jurisdiction or place of residence in a timely manner. 2. After the patients are discharged from the hospital, due to the low immune function of the body during the period of recovery, the patients have the risk of being infected with other pathogens, and it is recommended that they should continue to be treated. pathogens, it is recommended that they should continue to monitor their own health status for 14 days, wear masks, live in well-ventilated single rooms if possible, reduce close contact with family members, eat separate meals, practice good hand hygiene, and avoid going out for activities.3. It is recommended that patients should come to the hospital for follow up and re-examination in the 2nd and 4th weeks after discharge. Source: Medical Affairs and Healthcare Bureau Recruitment for this sudden epidemic everyone has their own “battlefield” to do their best to jointly combat the impact of the battle even small efforts multiplied by 365 are very obvious even big difficulties divided by 365 are very simple to have to come to the doctor of medical editorial talent recruitment is underway! This spring, good news will surely come with you as promised! Long press to recognize the QR code below to see the job details if you are interested in this position can add the QR code below to chat!