The main manifestations of type 1 neurofibromatosis are milky cafe au lait spots on the skin, multiple neurofibromas, and some patients may also invade the nervous system, bones, viscera and other organs.
1. Cafe au lait spots on the skin: multiple cafe au lait spots on the body surface are usually the early manifestation of type 1 neurofibromatosis, mostly occurring in the armpits, groin and other parts of the body, with regular shape, oval shape, and clear boundary of the cafe au lait spots, and the specific manifestations are related to the age and the individual to a certain extent.
2. Multiple neurofibromas: Neurofibromas in type 1 neurofibromatosis are usually multiple, pink or skin-colored, and soft in texture.
3. Skeletal system: Some patients may also have abnormal bone development, such as dysplasia of the long bones or scoliosis, etc. Patients with type 1 neurofibromatosis need to undergo regular bone growth examinations.
In addition, type 1 neurofibromatosis may have rare clinical symptoms such as high blood pressure, learning disabilities, memory loss, and seizures. The clinical features of the disease are highly variable and can result in disfigurement or dysfunction, with an increased risk of tumor malignancy, which can have a serious impact on the patient’s quality of life.
Once diagnosed, the patient should seek immediate medical attention, and under the guidance of the doctor, rational treatment should be carried out, and if necessary, surgical plastic surgery can be used to reduce the impact of the disease on the appearance, and reduce the inconvenience of life.