Methylphenidate Hydrochloride Extended-Release Tablets are a central nervous system stimulant that can be used in the treatment of attention deficit hyperactivity disorder in children and adolescents 6-17 years of age, as well as in adults, and also as a treatment for episodic somnolence and refractory depression. It can increase the activity of norepinephrine, especially dopamine, which improves concentration, attention, executive function, and arousal function, as well as depression, fatigue, and sleep thinking. Adverse effects of methylphenidate include autonomic dysfunction, as well as central nervous system adverse effects such as tremor, tachycardia, hypertension, insomnia, agitation, and even psychotic symptoms, which often require dosage adjustments or switching to other mechanisms of medication.