Oxygen is scarce at high altitude, and long-term living will result in a certain degree of hypoxia. Long-term hypoxia will lead to pulmonary hypertension, which in turn causes cardiac hypertrophy.
High altitude, due to the air density is small, the people living in this place is very easy to hypoxia. In the state of hypoxia, the body in order to meet the normal supply of oxygen, the heart rate will be compensatory increase in heart rate.
In addition, long-term hypoxia is likely to lead to spasm of the pulmonary artery, inducing an increase in pulmonary artery pressure. Long-term elevated pulmonary artery pressure will start the body compensatory mechanism, that is, by increasing myocardial contractility to pump blood into the pulmonary artery, but this move will increase the burden on the right ventricle, causing right ventricular hypertrophy.
Plains people go to live at high altitude, the first thing to consider the problem of hypoxia, hypoxia is easy to cause pulmonary hypertension and hypertrophy of the right ventricle, so the people to high altitude areas need to regularly inhale oxygen, to minimize the damage of hypoxia on the organism.