Inflammation of lymph nodes usually refers to lymphadenitis, patients need to follow the doctor’s instructions to use antibacterial drugs, antipyretic and analgesic drugs and antiviral drugs, such as penicillin, ibuprofen, ganciclovir and so on. 1. Antibacterial drugs: usually patients need to follow the doctor’s instructions oral or injectable antibiotic treatment, commonly used drugs are penicillin sodium, roxithromycin, cefadroxil and so on. The patients need to carry out skin test before using penicillin and cephalosporin, which is prohibited for allergic patients and should not be combined with tetracycline, chloramphenicol, erythromycin and other drugs. Alcohol is prohibited during the use of medication. 2 antipyretic and analgesic drugs: usually patients can follow the doctor’s instructions for external use of ketoprofen gel, so as to relieve pain, but children should be used with caution. Some patients can also take oral compound acetylsalicylic acid, ibuprofen and other antipyretic treatment. 3. Antiviral drugs: If patients have infectious mononucleosis caused by EBV infection, they can be treated with antiviral drugs such as ganciclovir and injectable adenosine monophosphate as prescribed by doctors. It is recommended that patients with lymphadenitis strictly follow the doctor’s instructions to use medication, and if necessary, also need to actively cooperate with the doctor for surgical treatment.