The most common cause of a stinging urethra with pus is a urethritis. UTIs can be divided into gonococcal urethritis and non-gonococcal urethritis. The clinical manifestation of gonococcal urethritis is relatively serious and the pus flowing out is more viscous, so it is recommended to use ceftriaxone injection for anti-infection treatment. In non-gonococcal urethritis, the pathogen is often mycoplasma or chlamydia, and the clinical symptoms are lighter and the pus is thinner than in gonococcal urethritis. Clinical treatment is recommended with tetracycline antibiotics, such as minocycline or doxycycline. The UTI can be transmitted between husband and wife through sexual contact, so if one of the spouses has symptoms of UTI, both spouses need to come to the hospital at the same time to be treated, and only by treating both spouses together can the inflammation be avoided due to cross-infection and repeatedly stay untreated.