Typical case: A patient developed a chronic wound after postoperative radiotherapy for a lipoma in a certain area. The wound did not heal and there was constant yellow fluid oozing out, and the symptoms did not improve after several months of continuous medication changes. This condition is typical of a chronic wound caused by radiotherapy. Radiotherapy wounds are one of the common slow wounds nowadays, especially with the high incidence of cancer, such cases are becoming more and more common. Here, I will briefly discuss the etiology and treatment of radiation wounds. During radiotherapy, after a period of irradiation, one of the causes is that the blood vessels in the irradiated area will start to sclerosis, which will restrict the blood flow to a certain extent, then the blood oxygen saturation of local tissues will decrease, the ability of the wound to control infection will decrease, and the wound will gradually expand and become necrotic due to the lack of nutrients for a long time. For this cause, it is very crucial to rebuild the local blood circulation, but how exactly? In this case, the infected, inflammatory and necrotic tissues need to be cleared first to provide conditions for the next step of granulation and revascularization. After that, I personally still recommend a combination of Chinese and Western medicine for treatment, with conventional Western medicine just for infection, supportive treatment, etc., while Chinese medicine still uses Chinese ointment with the effect of removing decay and regenerating muscle to apply externally to the treated wound, which is similar to the treatment idea of diabetic foot, bedsore and other slow trauma! Moreover, some patients will be relatively less difficult to treat compared to diabetic foot, because there is no serious lower extremity vascular occlusion problem and often localized lesions. Of course, wound treatment is one of the aspects, the physical condition of cancer patients is often complex as well, both physically and psychologically, and these can directly or indirectly affect the treatment outcome. Therefore, compared with the mature and well established multidisciplinary joint treatment model such as diabetic foot, the participation of oncologists is more necessary to jointly develop a comprehensive and personalized treatment plan for patients.