High CA125 single item needs to be taken seriously, which may be related to ovarian cancer, cervical cancer, breast cancer and some other benign diseases. It is recommended that the patient should go to the hospital in time to improve the relevant examination. Ovarian cancer: Ovarian cancer may have symptoms such as abdominal pain, abdominal distension, nausea, abdominal mass, ascites and so on when it develops. In the later stage of ovarian cancer, CA125 may be elevated, which is usually not considered high in the early stage. Cervical cancer:Early stage may have no obvious symptoms, and some patients may have symptoms such as increased vaginal discharge and vaginal bleeding. A single elevation of CA 125 can be seen during CA 125 examination. Breast cancer: mainly manifested as breast lumps, nipple and areola changes, breast skin changes, nipple milk overflow and other symptoms. A single elevation of CA 125 may be present on examination. The single elevation of CA 125 may be related to certain benign and malignant tumors, and at the same time, it may not be related to the disease. It is recommended that the patient go to the hospital in time to improve the relevant examination, to clarify the cause of the disease, and to treat the cause of the disease.