Eating pomegranate on an empty stomach can lead to irritation of the gastric mucosa, increased secretion of gastric acid, constipation and other bad effects. Pomegranate is a common fruit, which is not only rich in nutrients, but also has the effect of astringent intestine and diarrhea, inhibiting the reproduction of bacteria, which has a therapeutic effect on diarrhea, dysentery and other diseases. However, it is best to eat pomegranate about half an hour after a meal, and avoid eating it in an empty stomach. Because pomegranate is cold and tastes sweet and sour, eating it on an empty stomach can cause some irritation to the gastric mucosa, and patients with gastritis and gastric ulcer can also experience stomach discomfort. Pomegranate has the effect of promoting the secretion of gastric acid, which not only leads to acid reflux and belching, but also induces the onset of stomach diseases when there is excessive secretion of gastric acid. Since pomegranate is astringent to the intestines, eating it on an empty stomach can also cause slow intestinal peristalsis and even constipation.