Patients with triple positive are usually patients with chronic viral hepatitis B. Blood test for hepatitis B triple system suggests that patients are positive for hepatitis B surface antigen, hepatitis B e antigen and hepatitis B core antibody, which is mostly considered to have viral replication, and blood test for hepatitis B DNA mostly suggests that patients are positive for hepatitis B DNA. However, if the liver function of the patient shows no elevation of ghrelin and ghrelin transaminase, it is suggested that the patient should continue to observe without antiviral treatment, and the effect of applying antiviral drugs is not good, and it is necessary to carry out the liver function test on a regular basis, and the liver function should be examined by blood sampling every two to three months. In the later stage of the disease, when the liver function indicates that there is an elevation of ghrelin and ghrelin aminotransferase, it should be considered that the patient is in the window period of viral replication, and it is necessary to actively consider antiviral therapy and hepatoprotective therapy, and it is possible to consider oral antiviral drugs, such as entecavir and tenofovir, and it is possible to consider injecting interferon to carry on the active antiviral therapy.