After the syphilis is cured, syphilis specific antibody positive, syphilis non-specific antibody negative, there is no contagious. Syphilis is a chronic systemic sexually transmitted disease caused by syphilis spirochete infection, after syphilis spirochete infection of the human body, it can enter the bloodstream to spread to the whole body organs, skin mucous membranes, and a variety of bodily fluids, so the contagiousness is very strong. The standardized expulsion treatment, such as the use of penicillin and other sensitive antibiotics, a full course of treatment, the full dose of treatment, the body of the syphilis spirochete is the vast majority of can be killed, the patient infectiousness can be gradually declined, or even completely disappeared. After the human body is infected with the syphilis spirochete, the body will also produce a variety of antibodies against it, through the antibodies can confirm the diagnosis of syphilis and can monitor the changes in the condition of syphilis, non-specific syphilis antibodies are often positively proportional to the syphilis disease activity. Generally speaking, after treatment, the non-specific antibody titer will gradually decline to negative, the higher the titer, usually indicates that it is more infectious, the titer to negative usually think that the body of the syphilis spirochete has been completely killed, there is no longer infectious. Part of the patient drive plum treatment is not standardized, serum titer maintained at a certain titer, belong to the serum fixed situation, also not infectious. In short, syphilis is a curable sexually transmitted disease, the pathogen can be completely killed, become non-infectious.