After taking cephradine it is usually at least 3 days after stopping the medication before you can drink alcohol again because cephradine produces a disulfiram-like reaction with alcohol.
The half-life of cephradine is usually between 6 and 8 hours, and it usually takes 5 half-lives for the drug to be fully metabolized by the body. So usually it takes 2 to 3 days for cephalosporin antibiotics to be metabolized.
Cephalosporin and alcohol induced disulfiram reaction such as nausea and vomiting, generalized flushing, headache, drowsiness, blood pressure drop, and even shock, etc., generally more than 3 days in the body of the basic metabolism of the body, drinking alcohol may not produce adverse reactions, but suffering from some kind of liver and kidney disease or their own metabolism is slow, there may still be residual residual traces of the drug, can also be disulfiram reaction with alcohol.
Different patients have different liver and kidney functions, and the time needed for metabolism is not exactly the same. In patients with liver or kidney insufficiency, liver or kidney dysfunction, the time required for metabolizing the drug may take longer, possibly more than a week.
All in all, for safety reasons, each patient should analyze the specific situation according to the actual specific circumstances, and the use of medication should be in accordance with the doctor’s instructions.