When transaminase 146u/L is present, alcohol should generally not be consumed to avoid aggravating a pre-existing condition. The normal value of transaminase is usually around 0 to 40u/L. When there is transaminase 146u/L, it suggests the existence of liver injury. As the metabolites of alcohol contain acetaldehyde and other harmful substances, which can cause transaminase elevation, when patients with elevated transaminase consume alcohol, it may aggravate the burden on the liver and further aggravate liver injury. When patients have elevated transaminases, they should go to the hospital in time for examination to clarify the cause of the disease. If the transaminase is elevated due to overwork, patients can take proper rest and review the liver function regularly. However, if the transaminase is elevated due to hepatitis, cirrhosis, etc., the patient should choose the appropriate treatment according to the actual condition under the guidance of the doctor. When the transaminase is high, you should quit drinking strictly and go to the hospital for examination in time, do not be negligent to avoid delaying the condition and leading to adverse consequences.