Slow heart rate and weakness in sleep can be treated with nutritive cardiac medication and heart rate stimulation according to the cause. 1. Nutrition of the heart muscle: slow heart rate and weakness is considered to be caused by myocardial ischemia, so it is recommended to give nutrition of the heart muscle of the drug, such as isosorbide mononitrate tablets and other treatments. 2. Heart rate boosting treatment: If the heart rate is slow and weak in bed, and there is no obvious myocardial ischemia or arrhythmia, you can follow the doctor’s instructions to give heart rate boosting drugs, such as belladonna tablets, etc. for oral administration. Conduction block and sinus node dysfunction can also cause slow heart rate and weakness, and require targeted treatment, such as the installation of pacemakers. You should go to the hospital in time, according to the patient’s condition, choose the appropriate treatment, so as not to miss the condition.