Neonatal hypertrophic cardiomyopathy can be diagnosed and treated by the following measures: First, lifestyle, pay attention to more bed rest, breastfeeding should pay attention to the heart should not be too much preload aggravation; Second, the need for electrocardiographic monitoring, blood pressure monitoring, blood oxygen monitoring, if there is cyanosis of the lips and skin pallor, and oxygen saturation is low, it is necessary to give a sustained low-flow oxygen therapy, to give the cardiac monitoring process, if there is blood pressure stability, heart rate stability should be promptly symptomatic treatment. If there is unstable blood pressure and unstable heart rate, it should be treated symptomatically. If the blood pressure is low or even there are shock symptoms, give dopamine and other antihypertensive drugs, and adjust the drip rate of dopamine according to the blood pressure situation; Third, timely symptomatic treatment, it is not suitable for immediate surgery, we should wait for the condition to stabilize, and then carry out surgical treatment when the age is 2-4 years old.