Toothache in the afternoon and evening may be a manifestation of pulpitis, and timed pain may be caused by local irritation, environment, psychological factors, etc. It is recommended to go to the hospital for timely examination and treatment. Pulpitis is an inflammatory lesion of the pulp tissue, and when the blood vessels in the pulp cavity are dilated and congested, and the pressure is too great, there will be pain manifestations. Pulpitis is mainly manifested as cold and hot temperature irritating pain, acute pulpitis and spontaneous pain, and the pain is more intense. Toothache in the afternoon and evening may be due to the contact with hot and cold stimulation of tooth pain; may be due to the morning busy ignore the pain, afternoon and evening environment is quieter, relax and feel the pain; may also be caused by psychological factors. Pulpitis should be examined and treated in a timely manner, and usually cannot be cured on its own.