Side effects of valsartan amlodipine tablets may include nausea, dizziness, excessive sweating, diarrhea, back pain, insomnia, eczema, nasopharyngitis, arthralgia, hypotension, peripheral edema, sensory abnormalities, and upper respiratory tract infection. Valsartan amlodipine tablets is a compound preparation, consisting of two drugs, valsartan and amlodipine, which exerts antihypertensive effect by antagonizing the action of calcium channels and angiotensin Il, and can be used for the treatment of essential hypertension. When this drug is combined with potassium-preserving diuretics such as spironolactone and amlodipine, there will be situations such as elevated blood potassium concentration, so patients’ blood potassium should be closely monitored; when combined with lithium, blood lithium concentration should also be monitored. When the drug is combined with cyclosporine, rifampicin, ritonavir and other drugs, it may increase the blood concentration of the drug. It is contraindicated in the following cases: hypersensitivity to the drug, pregnant and lactating women, hereditary angioedema, patients with angioedema that occurs at an early stage after the use of angiotensin II receptor antagonists (ARBs) or angiotensin-converting enzyme inhibitors (ACEIs), patients with type 2 diabetes mellitus taking aliskiren, and patients with severe renal insufficiency taking aliskiren with a GFR <30 ml/min. Patients with renal insufficiency. Use with caution in the following conditions: severe renal impairment, arterial stenosis resulting in loss of function of one kidney, unilateral or bilateral renal artery stenosis, presence of biliary obstructive disease or mild to moderate hepatic impairment. If you need to use the drug, please strictly follow the doctor's instructions under the guidance of the medication, do not self-medication.