Hydroxymetazoline Hydrochloride Spray is an over-the-counter ENT medication that may cause drug-induced rhinitis after prolonged use. The role of hydroxymetazoline hydrochloride spray is mainly to treat acute and chronic rhinitis, hypertrophic rhinitis, allergic rhinitis caused by nasal congestion and edema, the drug’s adverse effects are mainly too frequent use of the drug is easy to cause rebound nasal congestion, prolonged use may cause drug rhinitis. It should be noted that patients with hypertension, diabetes mellitus, hyperthyroidism, coronary artery disease and other patients should be careful to use the drug. Patients use the drug as prescribed by the doctor and strictly follow the scientific dosage. It is recommended that patients should consult a medical professional before using the drug. If any discomfort occurs during the use of the drug, consult a doctor promptly.