Thinning of renal parenchyma is usually not self-healing, but may partially recover if the lesion is short-lived and the cause is removed. The causes of thinning of renal parenchyma may be congenital stenosis, renal pelvis stones, chronic renal failure, etc. 1. Congenital stenosis: for example, severe congenital stenosis at the junction of renal pelvis and ureter, the stenosis will become more serious with age, the hydronephrosis will become more and more serious, and the pressure on the renal parenchyma will become more serious, resulting in atrophy and thinning of the renal parenchyma, and irreversible damage, which is usually not curable. 2. Renal pelvic stones: Larger renal pelvic stones may obstruct the urine from the kidney to the bladder, increasing the intrarenal pressure, dilating the renal pelvis and calyces, and atrophying the renal parenchyma, thus causing thinning of the renal parenchyma. If the obstruction is not long, active treatment is needed, and partial recovery may be possible after the obstruction is lifted, but it usually cannot be cured by itself. 3. Chronic renal failure: usually caused by glomerular fibrosis and tubular atrophy. These lesions are a chronic process, usually irreversible, and the thinning of renal parenchyma caused by chronic renal failure is also difficult to recover through active treatment, and even more so, it cannot be cured by itself. The thinning of renal parenchyma usually indicates that the kidney structure is beginning to be damaged, and it is necessary to go to regular hospitals for medical treatment in time to avoid aggravating the condition and causing adverse effects.