Feeling drained and especially tired may be due to over-exercise, mental stress and abnormal thyroid function, which need to be analyzed specifically. 1. Excessive exercise: appropriate exercise is good for health, but too much exercise will give a person a feeling of overdraft, feel the whole body has no strength, feel very tired. 2. Mental stress: the spirit is in a state of tension for a long time, stress, will consume the body’s energy, resulting in fatigue. Therefore, you will feel weak and especially tired. 3. Abnormal thyroid function: abnormal thyroid function, such as hypothyroidism, the level of thyroid hormone secreted by the body will be reduced, which will lead to general weakness, feeling very tired and fatigue. If patients feel weak and tired, they should go to the hospital for relevant examinations to identify what causes the problem, and then give corresponding adjustments and treatments.