Conditions that qualify for third generation IVF are clearly diagnosed genetic disorders or chromosomal abnormalities, and severe genetic susceptibility disorders. Third-generation IVF is a method of in vitro fertilization-embryo transfer (IVF-ET) technology in which embryos are genetically or chromosomally tested prior to transfer in order to screen for normal embryos for transfer. The indications for third generation IVF are clearly diagnosed single gene disease or chromosomal abnormality, suffering from severe disease with genetic susceptibility, unexplained recurrent spontaneous miscarriage, or more than 2 failed transplants. Third-generation IVF is a genetic test before embryo transfer, which can effectively avoid the birth of fetus with single gene disease or chromosomal abnormality, and also ensure the quality of pregnancy. After the transfer, we should follow the doctor’s instructions to take proper rest, increase diet and nutrition appropriately, avoid strenuous exercise, and carry out blood or urine pregnancy test measurement about 2 weeks after the transfer to confirm pregnancy.