Umbilical cord blood is generally not used to treat myeloma, which uses autologous transplants. Umbilical cord blood is the blood that remains in the placenta and umbilical cord when the umbilical cord is cut after a pregnant woman gives birth to her fetus. As one of the sources of hematopoietic stem cells, umbilical cord blood is used for hematopoietic stem cell transplantation to treat some hematological disorders, such as leukemia, by differentiating into different cells, which in turn rebuilds the hematopoietic and immune systems of the body. The advantages of umbilical cord blood are rich content of hematopoietic stem cells, no contamination, low rejection reaction to the organism, and high regenerative capacity. Myeloma is a disease caused by malignant proliferation of plasma cells in the immune system. It can be treated by autologous hematopoietic stem cell transplantation to rebuild the patient’s hematopoietic function, alleviate the condition and prolong the survival period. If myeloma occurs, it is recommended to seek medical treatment in time and choose the appropriate method of treatment under the guidance of specialized doctors.