Whether to do intervention or immunization first for liver cancer needs to be based on the specific condition, generally through the treatment may be performed after surgical resection or ablation therapy. If there is no contraindication to intervention, intervention can be done first, and severe liver dysfunction can be treated with immunotherapy first. The treatment of liver cancer is mainly based on surgery, and those that can be resected should be resected as much as possible, if they cannot be resected, they may be resected after adjuvant therapy according to the condition, and if the liver function damage is not serious, they may consider interventional therapy first. If the liver cancer is in advanced stage, cannot be resected by surgery and is accompanied by serious liver dysfunction, immunotherapy can be considered, but the efficacy of immunotherapy is slow. Whether to do intervention or immunotherapy first for liver cancer should be judged by doctors according to symptoms, signs and auxiliary examination results.