Urobilinogen tests are negative or weakly positive in normal healthy people. Urobilinogen positivity is generally indicative of abnormalities, mostly seen in hemolytic jaundice, hepatocellular jaundice, heart failure, sepsis, neonatal hemolysis and other diseases. The patient’s liver is damaged and the reabsorption of urobilinogen is weakened, resulting in a positive urobilinogen. If diagnosed, patients with hemolytic jaundice can be treated with glucocorticoids, such as prednisolone and prednisone acetate, and if glucocorticoids are not effective, they can also be treated with immunosuppressants such as cyclosporine and cyclophosphamide; 2. Hepatocellular jaundice: After the disease, due to the damage to the liver cells, they are unable to convert urobilinogen, and the urobilinogen absorbed into the blood by the intestine needs to be excreted through the kidneys, resulting in positive urobilinogen in the urine . If diagnosed, patients with hepatocellular jaundice can use drugs such as reduced glutathione to alleviate liver function abnormalities, thereby improving the symptoms of urobilinogen positivity; 3. Heart failure: If a patient has heart failure, especially right heart failure, this can lead to liver stasis, resulting in liver function damage causing urobilinogen positivity. At this time, patients can use diuretics such as furosemide to improve fluid retention, and can also use digoxin, nitroglycerin and other drugs to maintain the ventricular rate and relieve the symptoms of heart failure; 4, sepsis: suffering from sepsis, can lead to organ and tissue degeneration, the liver may be enlarged, liver function is damaged, urobilinogen can appear positive performance at this time. The treatment of sepsis requires the early use of ceftazidime, ampicillin, penicillin and other antibiotics to control the symptoms, and later the medication can be adjusted according to the efficacy, bacterial culture and drug sensitivity results; 5, neonatal hemolysis: after suffering from neonatal hemolysis, due to the destruction of red blood cells caused by increased bilirubin, can indirectly cause urinary bilirubinogen elevation, appearing positive performance of urinary bilirubinogen. Neonatal hemolysis can be treated with intravenous injection of albumin, immunoglobulin and liver enzyme inducers, and can also be treated by light therapy.