Hiccups caused by physiological factors are usually not serious, but if they are caused by gastric ulcer, gastric cancer and other diseases, they are usually more serious. 1. Physiological factors: if the hiccups are caused by overeating, catching a cold in the abdomen, or swallowing a lot of gas when talking during meals, they can be relieved by themselves after a period of time, and are generally not serious. 2. Gastric ulcer: if the hiccups are caused by gastric ulcer, it is usually more serious, and the untimely treatment of this disease may lead to gastrointestinal hemorrhage, which is life-threatening. 3. Gastric cancer: hiccups for a day may be caused by gastric cancer, which is also more serious, and if it is not treated in a standardized way, distant metastasis may occur, leading to multi-organ failure. Clinically, there are many reasons for hiccups, so it is recommended to go to the gastroenterology department of hospital as soon as possible, to clarify the reasons for hiccups, to accurately determine the severity of the disease and to follow the doctor’s instructions to standardize the treatment.