Erythrodermic diseases, including erythrodermic psoriasis, etc., do not matter the most effective treatment, should actively control the symptoms and improve the quality of life of patients. When erythrodermic psoriasis occurs, there is diffuse flushing of the skin all over the body, which may be accompanied by a large number of furfuraceous scales, and its course is long and easy to recur, and the current psoriasis treatment can only achieve the recent effect. For the treatment of erythrodermic psoriasis, we can use retinoic acid drugs such as Avicenna to start taking in small doses, and we can also use hydroxyurea as the third line of treatment, in addition, we can use glucocorticosteroids such as prednisone to reduce the acute lesions, and tretinoin has a better efficacy for this disease. After the occurrence of erythrodermic psoriasis, actively seek medical advice, standardized treatment under the guidance of the doctor, the use of a variety of methods of combined treatment to increase the efficacy of treatment.