Microscopic lesion nephrotic syndrome has a certain probability to develop into uremia, but this is less common. Microscopic lesion nephrotic syndrome is a primary glomerular disease with the pathological type of microscopic lesion nephropathy, which is characterized by fatty degeneration of epithelial cells of proximal tubules without mesangial cell hyperplasia, stromal widening, and immunodeposition.
Microscopic lesion nephropathy is characterized by natural remission and recurrent flares. Generally, most of the microscopic lesion nephropathy has a good prognosis after active treatment. However, if it is not treated in time or the treatment is not effective, further complications may occur, such as acute kidney injury.
When acute kidney injury causes severe blood volume drop, it shows the characteristics of acute renal failure such as oliguria or anuria, decreased urinary sodium, and increased hematocrit. Due to the acute impairment of renal function, or repeated episodes of turning into chronic kidney disease, it may eventually lead to the occurrence of uremia.
Therefore, patients diagnosed with microscopic lesion nephrotic syndrome should go to the hospital in time and actively cooperate with doctors to relieve clinical symptoms and control the development of the disease.