There is no clinical study to prove that long-term daily consumption of simvastatin is harmful; however, the consumption of simvastatin can cause adverse reactions, overdose can lead to toxic reactions, clinical should be under the guidance of a physician to take this drug. Simvastatin is a lipid-regulating and anti-atherosclerotic drug, used for the treatment of hyperlipidemia, coronary heart disease, etc.; this product can cause nausea, diarrhea, rash, dyspepsia, transaminase elevation, myalgia, myositis, and other adverse reactions, so it is recommended to carry out the liver function test as well as the creatine kinase test after the treatment; an overdose of this drug can lead to toxic reactions. It is contraindicated for those who are allergic to the product, those with active liver disease, women of childbearing age, pregnancy, breastfeeding, and those with severely impaired liver function; it is used with caution in those who consume alcohol and have renal insufficiency. If you need to take simvastatin, you should go to the hospital in time, actively cooperate with the doctor’s treatment plan, follow the doctor’s instructions, do not blindly take the drug on your own.