Biliary tract motility dysfunction manifests as abdominal pain, which is paroxysmal colic in the upper abdomen or right upper abdomen. Some patients may have nausea and vomiting, which can be triggered by eating fatty foods and often lasts for 2 to 3 h. The symptoms are relieved with antispasmodics. The movement of the biliary system is influenced by a variety of factors both inside and outside the body. Under normal conditions, the bile flow in the extrahepatic bile duct can be influenced by some intrinsic factors as follows: 1. the pressure of hepatic bile secretion, the pressure in the bile duct. 2.The amount of hepatic bile. 3.The degree of bile duct closure. 4.The elasticity of the gallbladder wall, the tone and contraction function of the gallbladder muscle. 5.Concentration function of gallbladder, viscosity of bile. 6.Tension and reactivity of bile duct sphincter. 7.Tension and movement of the duodenal wall. 8.Closure of the duodenal papilla. 9.The effect of peristalsis and movement of other parts of the digestive tract on the biliary system. 10.The release amount, transit efficiency and inactivation rate of cholecystokinin.