Anal papilloma does not necessarily need to be removed, need to be based on the condition under the guidance of the doctor to choose the appropriate treatment. Anal papilloma is a kind of benign tumor occurring in anal canal, mostly due to the proliferation, hypertrophy and hardening of anal papillae under long-term stimulation of feces or chronic inflammation, which can be detached out of anus with defecation, and sometimes there will be symptoms such as blood after defecation, feeling of impurity in defecation, and itching in anus. The treatment of anal papilloma is divided into general treatment, drug treatment and surgical treatment. Surgical excision is suitable for patients who are ineffective in general treatment and medication, or those with severe anal papilloma hypertrophy. For early anal papilloma, general treatment is available. General treatment includes drinking more water, increasing dietary fiber intake, avoiding spicy and stimulating food, taking sitz bath with 1:5000 potassium permanganate solution every day, and defecating regularly. Drug treatment includes the symptomatic use of drugs under doctor’s guidance, such as oral laxative lactulose to regulate constipation; external use of hemorrhoidal suppository or hemorrhoidal ointment and other drugs to reduce inflammation and swelling; local analgesic drugs, such as Lidocaine gel paste and other treatments. Anal papilloma in the above symptoms and treatment such as no relief, anal papilloma obvious hypertrophy and affect defecation, etc., can be given to surgical resection treatment, comply with the doctor’s instructions, and actively cooperate with the postoperative care of medication, to achieve a good prognosis.