Children with chronic granulocytic leukemia, especially patients over 2 weeks of age, the onset of patients are few, the prognosis is very poor, I contacted the pediatric patients prone to acute change, Gleevec efficacy is not good, it is recommended to do allogeneic hematopoietic stem cell transplantation. It is technically possible to cross the HLA incompatibility barrier and receive the China Medical Science and Technology Award, the following points should be considered 1. 2, domestic can successfully do 2 weeks old children hematopoietic stem cell transplantation, I think most of the units are difficult or inexperienced, children are small, care is a challenge, I am able to say that we completed 1-2 years old cases transplanted several cases. 3, I think transplantation is the best method, choose non-blood or semi-identical parent donor, both are considered, if the non-blood high resolution results are good, more first consideration 4, transplantation success rate will be very high, after transplantation relapse situation I can not say, adult chronic granulocytic leukemia transplantation relapse lowest, because the graft anti-leukemia strongest, but children 2 years old, I estimate that the country is the smallest child chronic granulocytic leukemia transplantation The results of the transplant, but the choice of transplant should be indicated for sure.