Many patients on the Internet have asked me about whether they can have children with high blood pressure. Whenever I am confronted with such patients, my heart is always very heavy. I know what it means for a woman to be pregnant, but because of her high blood pressure, I know how great a risk she faces in becoming pregnant. Although there are many antihypertensive drugs available, strictly speaking, none of these drugs have been clinically studied for use in pregnant women. There are several drugs that are publicly stated not to be used in pregnant women, such as prilosec and sartans, like captopril and irbesartan, which have been found to have side effects that cause fetal malformations in animal studies, so the instructions clearly state that they are prohibited in pregnant women; diuretics, such as tachyphylaxis, can cause fetal hypoxia; beta receptor blockers can lead to fetal growth retardation and slowed heart rate; some calcium channel blockers have instructions that clearly state that they are prohibited for pregnant women. Therefore, no drug is safe for pregnant women if they are to use antihypertensive drugs throughout pregnancy. For women who want to have children, I recommend that you use non-pharmacological therapies to control your blood pressure before you get pregnant, such as lifestyle modification, proper exercise, and weight control, to keep your blood pressure as low as possible at 140/90 mm Hg. During the first trimester of pregnancy, try not to take any antihypertensive medications. By the middle and later stages of pregnancy, while strengthening the monitoring of blood pressure, if the blood pressure exceeds 160/100 mm Hg and obvious symptoms appear, the blood pressure can be controlled temporarily with the use of diuretics, magnesium sulfate and other medications.