The first-line antihypertensive drugs currently used in clinical practice, among which dihydropyridine calcium channel blockers, beta-blockers and diuretics, all have certain effects on sexual function, among which the effects of beta-blockers may be large. In the clinical use of antihypertensive drugs for antihypertensive treatment, for relatively young male patients, should avoid the use of drugs that have a relatively large impact on sexual function. However, the effects of the above mentioned drugs on sexual function are temporary and sexual function can be restored if they are discontinued. For relatively young male patients, angiotensin-converting enzyme inhibitors, angiotensin II receptor antagonists, and non-dihydropyridine calcium channel blockers can be used, which have no effect on sexual function.