The mention of desensitization needle is rather vague, in fact, it is an anti-allergic drug, which is applied when the body is in various antigenic substances such as bacteria, viruses, pathogenic microorganisms, parasites and other metaplasia-mediated diseases caused by the immune system, also known as anti-allergic drugs, usually divided into the following four categories: first, the commonly used clinical isoprostanes, paracetamol belong to desensitization needle, also belongs to the antihistamine class of drugs; second, desensitization needle belong to a kind of anti-allergy mediator release drugs, can stabilize mast cell membrane, inhibit mast cell degranulation, such as sodium cromoglycate, ketotifen and other drugs; third, leukotriene receptor antagonists, representative drugs have montelukast sodium, mainly used in respiratory allergy, such as the treatment of allergic asthma; fourth, antigen-antibody complexes, such as epinephrine, adrenal glucocorticoids, commonly used drugs such as dexamethasone, methylprednisolone and other drugs. Fifth, allergen-specific immunotherapy, commonly known as desensitization therapy, is an allopathic approach to induce immune tolerance to allergens. Subcutaneous desensitization is commonly used, therefore, desensitization injections most likely refer to subcutaneous desensitization treatment