Possible causes of high serum iron include: iron utilization disorders, increased iron absorption (chronic hemolytic anemia, hepatitis, etc.), increased iron input (iron injections, etc.), and pregnancy. 1. Iron utilization disorder: lead poisoning, pernicious anemia and other diseases can lead to affect the utilization of iron, resulting in elevated serum iron levels. 2. Increased iron absorption: chronic hemolytic anemia, acute and chronic hepatitis, etc. can cause enhanced hematopoiesis leading to increased iron absorption, thus resulting in high serum iron. 3. Increased iron input: such as iron injection therapy (overdose) or blood transfusion can also lead to high serum iron. 4. Pregnant women: Pregnant women are prone to iron deficiency anemia, resulting in high serum iron. The above are some of the reasons for high serum iron. Serum iron fluctuates from time to time, so it is necessary to test it at the same time, and it should be treated actively under the guidance of the doctor after diagnosis.