Bile reflux causing pain in both the front and back of the chest may be caused by radiating pain produced by the lesions of internal organs such as pyloric dysfunction and cardia relaxation. 1. Pyloric dysfunction: Due to pyloric dysfunction, bile from the duodenum will flow back into the stomach and stimulate the gastric mucosa, which will cause gastric mucosal erosion and ulceration, leading to stomach pain, which may radiate to the chest and back and cause pain. 2. Cardia relaxation: when cardia can not play the role of anti-reflux well, bile and gastric acid reflux into the esophagus, and produce greater stimulation to the esophagus, it is easy to cause pain in the throat and esophagus, and the pain may radiate to the chest and back, causing pain in these parts. When patients experience bile reflux with anterior chest and back pain, it is recommended that they seek prompt medical attention to identify the cause of the condition under the guidance of a medical professional and take symptomatic treatment.