Compression of nerves in the spine may be caused by degenerative changes in the spine, trauma, and space-occupying lesions. Symptoms can be relieved by general treatment, physical therapy, medication and surgery to address the cause. 1. Degenerative changes of the spine: Long-term exertion, poor posture or aging may cause degenerative changes of the spine, such as spondylolisthesis, vertebral instability or slipped vertebrae, herniated discs, and so on, which may compress the nerves. Attention should be paid to rest and avoid exertion. Correct bad posture and cooperate with exercise. Traction, ultrasonic physiotherapy, infrared ray physiotherapy, etc., can be adopted for treatment. If necessary, surgery should be carried out. 2. Trauma: Spinal injuries caused by falls, impacts and other traumatic injuries may lead to spinal compression of nerves. If pain symptoms are obvious, oral non-steroidal anti-inflammatory drugs, such as ibuprofen and diclofenac sodium, can be taken to relieve pain. In case of fracture and misalignment, manipulation or surgical decompression is required. For open spinal cord injuries, early debridement and removal of broken bone fragments and foreign bodies in the spinal canal are the mainstays. 3. Occupying lesions: Occupying lesions of the spine, such as spinal bone tumor or intravertebral canal tumor, may lead to spinal compression of nerves. It is mainly treated by surgery. If necessary, adjuvant radiotherapy and chemotherapy. All the above medications should be used under the guidance of a doctor, avoid self-medication.