Diaper rash is an erythematous papular maceration of the skin around the infant’s buttocks and anus, accompanied by a degree of itching that needs to be actively managed. The cause of diaper rash in infants is mostly due to the fact that the diapers are not changed for a long time or the fabric is too hard, resulting in redness of the infant’s buttock skin damaged by more severe friction, coupled with the aggravation of symptoms and the growth of papular macules after infections such as Candida. For treatment, if the infant’s buttock skin is only red, some prickly heat powder or baby triple powder consisting of talcum powder and zinc oxide can be applied to help keep the skin there dry. When diaper rash occurs oozing or vesicles, apply gauze dipped in a certain percentage of boric acid solution to the affected area, remove the gauze when it is less watery, and apply some stove glycerin lotion to the area. For specific treatment, you should still consult a dermatologist or pediatrician to avoid making mistakes in medication and dosage, which may affect the infant’s recovery. In addition, the care of the infant’s buttocks is quite important. To reduce the occurrence of diaper rash, parents should change wet diapers in a timely manner, use more breathable fabrics, and not wrap the infant’s buttocks or sit on pads with plastic and other non-breathable materials to prevent leakage. In summer and other seasons when babies sweat a lot, they should use prickly heat powder or talcum powder in appropriate amounts. Wipe the baby’s bottom with moderate force, and after defecation, wash it with clean, warm water and then wipe it with a soft cloth. If the diaper rash is mild, first apply some triple powder to keep the buttocks dry. If there is oozing vesicles, then you need to use boric acid solution and furnace glycol, etc. to treat and strengthen the usual care of the baby’s buttocks.