The development process of chronic renal failure begins with infections and other diseases that damage the basement membrane of the body’s kidney, which is damaged for a long time, causing damage to the kidney units. The kidney units are about 800,000-1,200,000 or so. The kidney units cannot be regenerated and are constantly damaged, and the stock is constantly reduced. After the increase of damage, the kidney units are not enough to excrete toxins and metabolites compensated, which causes the elevation of serum urea nitrogen and serum creatinine, and enters about the third stage of chronic nephritis. As the serum creatinine continues to rise, it produces symptoms such as hypertension and anemia, and these factors in turn, a vicious cycle, aggravating kidney damage, aggravating kidney unit damage, and after the damage is called sclerosis of the kidney unit. As the sclerosis of the kidney unit increases, the serum creatinine becomes higher and higher, and the glomerular filtration rate decreases continuously in a delayed process, such as glomerular filtration rate below 15 ml/min, entering the uremic phase. Chronic nephritis is divided into five stages, at the beginning only need to control hypertension, proteinuria, such as elevated serum creatinine, suggesting further impairment of kidney function, impaired compensatory function, continuous damage, to the back of the basic loss of kidney function, that is, uremic syndrome.