① Infants born to serum HBsAg-negative mothers should receive the first 10 μg dose of recombinant hepatitis B vaccine within 24 hours after birth, and the second and third 10 μg doses of recombinant hepatitis B vaccine in the first and sixth months of life, respectively; ② Infants born to serum HBsAg-positive mothers should receive both the first 10 μg dose of recombinant hepatitis B vaccine and 200 IU of HBIG at different sites within 24 hours after birth and 200 IU of hepatitis B immunoglobulin (HBIG), and 1 month after birth, the first 10 μg of recombinant hepatitis B vaccine and 200 IU of HBIG should be administered simultaneously at different sites, and the third dose of hepatitis B vaccine should be administered in the sixth month of life: ③ It is wrong to give HBIG to pregnant women in the third month after pregnancy as it cannot block intrauterine infection and may even be harmful; ④ During pregnancy in HBsAg carriers Antiviral therapy for pregnant women is generally not advocated; however, in recent years, it has been reported that in the last 3 months of pregnancy, the use of pregnancy grade B NUCs, including tipifudin and tenofovir (also many scholars believe that lamivudine should be included) to block mother-to-child transmission is satisfactory, and no safety problems have been found.