Infection with H. pylori does not usually cause manifestations such as facial acne. H. pylori is a contagious bacterium, and infection with H. pylori can easily induce gastrointestinal-related diseases such as chronic gastritis, peptic ulcer and gastric cancer. Acne is generally referred to as acne. Acne is caused by a combination of factors, including Propionibacterium acnes infection, androgen levels, increased sebaceous gland secretion, and inflammation; in addition to dairy consumption, a high-sugar diet, high-temperature environments, late nights, or excessive psychological stress. There is no clear evidence-based medical evidence that H. pylori infection is directly related to the development of acne, so patients with H. pylori infection who develop facial acne can visit a hospital and be treated under the guidance of a doctor.