There is no best treatment for overactive bladder syndrome, which can be treated with training therapy and medication, and its treatment also includes surgery and other treatments. 1. Bladder training treatment (1) Drink more water during the day to lengthen the interval between urination and stop drinking after nightfall. (2) Bladder training also includes pelvic floor muscle training, biofeedback therapy and other behavioral treatments such as hypnotherapy. 2. Drug therapy (1) M receptor antagonists: such as atropine, oxybutynin, tolterodine, etc., of which tolterodine is currently the most selective effect on the urethral muscle tissue of the strongest drugs, fewer adverse reactions and better tolerated. (2) Sedative and anxiolytic drugs: such as promethazine and diazepam. (3) Prostaglandin synthesis inhibitors: such as indomethacin. (4) Calcium channel blocking drugs: such as verapamil, nifedipine. 3. Surgery: Surgical methods include forced urethral muscle transection, bladder auto-enlargement, and urinary diversion. 4. Other treatments (1) Bladder instillation: instillation of capsaicin, trehalose toxin, etc. It can be tried for severe bladder sensory hypersensitivity. (2) Botulinum toxin type A: it is effective for severe urethral instability. (3) Neuromodulation: sacral nerve electro-modulation therapy, effective for some patients. (4) Acupuncture treatment: Acupuncture on Guanyuan point, Sanyinjiao, Sanli and Qihai can relieve symptoms. Patients with overactive bladder syndrome should go to the hospital in time and standardize the treatment under the doctor’s guidance.